Aer Lingus Regional said it expects a large number of golf fans from North America to transfer through Dublin Airport on to Scotland to attend the tournament, which is now in its 145th year.
The airline will operate its larger 174-seater A320 on the route between July 11 and 19 to cater for the increased demand for seats from those travelling from Ireland and onward from cities including New York, Boston, Chicago and Toronto.
Martin Saxton from Stobart Air, operators of Aer Lingus Regional, said: "The additional capacity on the route is a direct response to the increased passenger demand amongst golf enthusiasts looking to attend the event and cheer on what is an exceptionally strong field of Irish golfers competing in this year's Open."
St Andrews was the venue for the 2015 Open, with American Zach Johnson winning the famous Claret Jug trophy.
Spectator admissions topped more than 237,000 over the course of the event, which generated an estimated £140 million for the Scottish economy.
The Open dates back to 1860 and is golf's oldest major championship.